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The homologous recombination pathway is frequently altered in advanced prostate cancer

Recent approvals of new treatments have led to improved outcomes for patients with advanced prostate cancer 1,2 However, metastatic disease remains aggressive and progression is inevitable. Mckay concluded her presentation discussing emerging frontiers in metastatic prostate cancer with the following take home points There have been significant advances in advanced prostate cancer treatment somatic tumor and germline sequencing is recommended for all patients with advanced disease The drug aims to extend the effectiveness of existing prostate cancer treatments such as hormone therapy. plasticity is a hallmark of cancer in general and a very important feature of advanced prostate cancer, particularly when it comes to the emergence of treatment resistance, says shen.

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