Photos of the osmosis jones (movie) voice actors. Cast credited cast chris rock as osmosis jones (voice) laurence fishburne as thrax (voice) david hyde pierce as drix (voice) Will smith was originally cast as the voice of osmosis jones, but withdrew from the project a few months before production started. Osmosis jones (2001) ← back to main cast 20 chris rock osmosis jones (voice) laurence fishburne thrax (voice) david hyde pierce drix (voice) Cast members details for osmosis jones Get actor roles, casting info, images and more
Explore the cast of characters, their bios and filmography.
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