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This topic will review the management, prevention, and prognosis of bacterial sepsis in preterm and term neonates, including neonates who remain hospitalized after birth and those who are admitted from the community within the first 28 days of life.

Neonatal sepsis refers to an infection involving the bloodstream in infants under 28 days old Sepsis in newborns (neonatal sepsis) is a serious medical condition that affects babies younger than 28 days old Sepsis occurs when your body has an extreme response to an infection A newborn who has an infection and develops sepsis can have inflammation throughout their body. This article will cover the recognition and management of both, as well as the pharmacist’s role in the prevention of these conditions. It occurs when the body’s immune system has an extreme response to the infection leading to organ dysfunction.

By synthesizing recent research findings and clinical practices, the review seeks to offer insights into the evolving landscape of neonatal care. Neonatal sepsis, a bloodstream infection in the first 28 days of life, is a leading cause of morbidity and mortality among infants in both developing and developed countries. Gardp published the findings in plos medicine in june 2023 and produced a report in 2022.

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